F




Reports and Activities

The Foundation received 21 applications for funding for 2007-2008, from 11 European countries, and 2 from outside Europe. Our grants board have selected these five studies for funding:

  • The preference of group-housed mice for different bedding materials
  • Monitoring the depth of anaesthesia in sheep
  • The validation of 50kHz ultrasonic vocalizations as an objective measure of welfare in laboratory rats
  • A novel method to ensure uniform dietary restriction in group housed laboratory rats
  • Assessing a novel restricted feeding method with respect to: animal welfare, appropriate number of animals and quality of research in long term studies with Wistar rats.
The Foundation received 21 applications for funding for 2006-2007, from 6 European countries, and 4 from the US. Our grants board have selected these four studies for funding:

  • Effects of social housing and testing order on novelty-induced behaviour in male & female mice of 3 strains to ensure a scientific basis for housing and husbandary standards
  • Reducing rat numbers by use of a purified diet instead of natural-ingredient diet
  • Assessing the impact of enriched housing conditions on rat welfare by investigating their anticipatory behaviour in expectation of a reward
  • Characterization of isoflurane and sevoflurane for anesthesia of mice and optimization of effective analgesia and balanced anesthesia
The Foundation received 8 applications for funding for 2005-2006, from 6 European countries, and one from the US. Our grants board selected three studies for funding:

  • Determination of minimum concentrations for loss of consciousness and abolition of reflex withdrawal during euthanasia with carbon dioxide
  • Refinement and reduction outcomes of specific enrichment items in laboratory rats
  • The effect of environmental enrichment on experimental infection in laboratory mice
The Foundation received 15 applications for funding for 2004-2005, from 9 European countries. Our grants board selected three studies for funding:
  • Impact of tail biopsy in the mouse - a pilot study
  • Impact of "living apart together" on post operative recovery on female laboratory mice compared to social and individual housing
  • Humane endpoints in cancer research - evaluation of biochemical and welfare parameters in rat models with hidden tumours
Several of these projects have been completed and are being submitted for publication. Presentations of the work have already started. These include:
  • Humane use of carbon dioxide for euthanasia to; Animal Welfare Officers in the UK, Secal Eslav meeting 2005, Spain (Abstract) ,Laboratory Animal Veterinarians in the UK
  • Refinement and reduction outcomes of specific enrichment items in laboratory rats to; American Association for Laboratory Animal Science 2006 Annual meeting (Abstract)
  • Impact of "living apart together" on post operative recovery on female laboratory mice compared to social and individual housing (Publication)
These studies cover the priority areas that were identified by the Foundation:

  • Refinement in experimental techniques, anaesthesia and analgesia to reduce pain and distress
  • Objective measures of animal welfare
  • Studies to ensure scientific basis for housing and husbandry standards
  • Validation of environmental enrichment to improve behavioural well being
The Foundation will make a further call for grant proposals for 2007-2008. Information on applying for funding is available, click the 'applications for funding' button.

The Foundation has Charitable status (UK Registered Charity no. 1104122)

2003 - 2004 www.eclameslavfoundation.org

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